Could Photobiomodulation Be a Powerful Add-On to Your Mental Health Journey?

At Eos we’re always exploring innovative approaches that can complement traditional therapy and offer new avenues for healing. One fascinating area that's gaining traction is Photobiomodulation (PBM), particularly transcranial photobiomodulation (tPBM). This cutting-edge technology uses specific wavelengths of light to stimulate cellular function, and emerging research suggests it could be a valuable "add-on" for those seeking to improve their mental well-being.

So, what exactly is PBM, and how might it support your mental health? Think of it as a gentle, non-invasive way to give your brain a boost. Here are some of the potential benefits being explored in current research:

Alleviating Symptoms of Depression: Studies indicate that PBM may be effective in reducing symptoms associated with depression, including major depressive disorder (MDD) and even treatment-resistant depression (Ji et al., 2024; Schiffer et al., 2009; Cassano et al., 2018). This offers a hopeful prospect for individuals who haven't found sufficient relief through conventional methods.

Reducing Anxiety: Research suggests that PBM could be a promising option for managing generalized anxiety (Maiello et al., 2019; Schiffer et al., 2009). Imagine a therapy that helps calm the nervous system at a cellular level.

Potential for PTSD Prevention: While still in early stages, preclinical animal studies have shown that specific types of tPBM may help prevent PTSD-like symptoms (Gao et al., 2023). This opens doors for exciting future research into early intervention.

Improving Cognitive Function: Beyond mood, PBM has shown promise in enhancing cognitive abilities such as memory and overall brain function (Saltmarche et al., 2017; Cheung et al., 2023). This could be particularly impactful for those experiencing "brain fog" or cognitive challenges related to mental health conditions.

How Does It Work? The Science Behind the Light

The magic of PBM lies in its ability to influence cellular processes. When red and near-infrared light are applied, they are absorbed by the mitochondria within your cells – the "powerhouses" responsible for energy production. This absorption triggers a cascade of beneficial effects:

Enhanced Cellular Energy: PBM can increase the production of ATP (adenosine triphosphate), the primary energy currency of cells, leading to improved cellular function (Glass, 2021; Nairuz et al., 2024; Cassano et al., 2018). More energy means your brain cells can function more efficiently.

Reduced Oxidative Stress and Inflammation: It helps to reduce cellular damage caused by oxidative stress and can decrease inflammation, both of which are implicated in various mental health conditions (Glass, 2021; Nairuz et al., 2024; Cassano et al., 2018).

Promoting Brain Health and Repair: PBM is thought to promote neurogenesis (the growth of new brain cells) and neuroplasticity (the brain's ability to adapt and reorganize), contributing to overall brain health and resilience (Nairuz et al., 2024; Cassano et al., 2018).

Improved Blood Flow and Connectivity: It can increase cerebral blood flow, ensuring your brain gets the oxygen and nutrients it needs, and may also modulate brain network connectivity, improving how different parts of your brain communicate (Nairuz et al., 2024; Cassano et al., 2018).

Activating the Brain-Gut Connection: Interestingly, some research suggests PBM can even activate the crucial brain-gut axis, highlighting the interconnectedness of our physical and mental health (University of Barcelona, 2024).

Important Considerations

While the potential of PBM as an add-on therapy is incredibly exciting, it's crucial to remember that it is still an emerging field. Many studies are preliminary, and larger, more comprehensive clinical trials are needed to fully establish its efficacy and standardize treatment protocols.

Our role is to help you navigate all available options. PBM is not a standalone cure but rather a promising tool that, when used responsibly and under professional guidance, could enhance the benefits of your ongoing therapy.

If you're curious about whether PBM might be a suitable addition to your mental health plan, I encourage you to discuss it with your healthcare provider or a qualified mental health professional. Together, we can explore how this innovative technology might illuminate your path to greater well-being.

References:

* Cassano, P., Petrie, S. R., Mischoulon, D., Cusin, C., Katnani, H., Park, L., ... & Iosifescu, D. V. (2018). Transcranial photobiomodulation for the treatment of major depressive disorder. Photomedicine and Laser Surgery, 36(12), 634-646.

* Cheung, M. C., Lee, T. L., Sze, S. L., & Chan, A. S. (2023). Photobiomodulation improves frontal lobe cognitive functions and mental health of older adults with non-amnestic mild cognitive impairment: Case studies. Frontiers in Psychology, 13, 1095111.

* Gao, S., Hu, K., Zhao, Y., & Li, Y. (2023). Preventing Post-Traumatic Stress Disorder (PTSD) in Rats with Pulsed 810 nm Laser Transcranial Phototherapy. Research Communities.

* Glass, D. (2021). Photobiomodulation and Mood and Anxiety Disorders: A Balanced Review. Psychiatry Redefined.

* Ji, Y., Wang, Z., Li, Y., & Wang, Q. (2024). Photobiomodulation improves depression symptoms: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Psychiatry.

* Maiello, M., Zomorrodi, R., Downar, J., & Daskalakis, Z. J. (2019). Transcranial photobiomodulation for generalized anxiety disorder: A pilot study. Brain Stimulation, 12(2), 527-529.

* Nairuz, R. H., El-Kholy, A. A., & El-Sayed, E. A. (2024). Photobiomodulation: shining a light on depression. PubMed Central.

* Saltmarche, A., Naeser, M. A., Ho, M. D., & Hamblin, M. R. (2017). Photobiomodulation for Improving Brain Function in Dementia (PBM Dementia). ClinicalTrials.gov.

* Schiffer, F., Johnston, A. L., Ravichandran, C., Webb, R. H., & Hamblin, M. R. (2009). Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety. Behavioral and Brain Functions, 5(1), 46.

* University of Barcelona. (2024). Activating Brain-Gut Connection with Light Reduces Depression. Neuroscience News.